Surprising insights into the role of autophagy in neuron

It appears that autophagy protects neurons in the brain, but for different reasons than previously assumed, as researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) and Charité in Berlin have now shown. When the scientists used a genetic trick to switch off autophagy-mediated cellular waste disposal, instead of detecting protein deposits, as expected, they found […]

Continue Reading

Parents, MDs agree: genome sequencing as first-tier diagnostic benefits infants in ICU

A vast majority of doctors and parents of babies in intensive care, with diseases of unknown origin, believe genomic sequencing is beneficial in managing care, according to two new papers published by Rady Children’s Institute for Genomic Medicine. The study examined the attitudes of parents and physicians of infants admitted to neonatal intensive care at […]

Continue Reading

Medicaid expansion linked to lower mortality rates for three major types of cancer

In states that have expanded Medicaid availability as part of the Affordable Care Act (ACA), mortality rates for three major forms of cancer are significantly lower than in states that have not expanded their Medicaid, a new study by researchers at Dana-Farber Cancer Institute, Brigham and Women’s Hospital, and Harvard University shows. Data from the […]

Continue Reading

NYCHA secondhand smoke policy needs more time and effort to show how well it works

One year into a smoking ban in buildings run by the nation’s largest public housing authority, tenant exposure to secondhand smoke in hallways, stairwells, and apartments has not declined, a new study shows. Among the explanations for this, investigators say, are delays in promotion and enforcement, including putting up signage and training building managers, and […]

Continue Reading

Large-scale cancer proteomics study profiles protein changes in response to drug treatments

Through large-scale profiling of protein changes in response to drug treatments in cancer cell lines, researchers at The University of Texas MD Anderson Cancer Center have generated a valuable resource to aid in predicting drug sensitivity, to understand therapeutic resistance mechanisms and to identify optimal combination treatment strategies. Their findings, published today in Cancer Cell, […]

Continue Reading

Scientists make breakthrough discovery of new therapeutic targets for Alzheimer’s

Researchers at the Hong Kong University of Science and Technology (HKUST) have identified new therapeutic targets for Alzheimer’s disease (AD) by studying the patients’ brain with a newly-developed methodology. This novel approach also enables researchers to measure the effects of potential drugs on AD patients, opening new directions for AD research and drug development. Although […]

Continue Reading